The platform consists of equipments, tools and methods necessary to proteomics studies and the development of methodologies required for protein biomarker research and more fundamental research on the mechanisms involved in cancer or other diseases. The main objectives of the platform are focused on the identification of peptides and proteins, the study of post-translational modifications and protein quantification from various, more or less complex samples (purified proteins, cell lysates, serum, plasma, secretome, tissues,.. ) and particularly clinical samples. The platform participates in the development of systemic approaches (Systems Biology and Systems Medicine), through research programs like SYSCLAD european project.
Several formations are organized by the scientific staff of the platform, from basic courses on proteins for undergraduated students to very specialized practical sessions for graduated students. Promethee platform is involved in the European Graduate School BioHealth Computing by organizing theoretical and practical proteomics courses and provide internships for master and PhD students.
The Prométhée Platform and Massomics Platform of the Biopark in Archamps Technopole signed in 2012 a partnership for joint developments.
The platform is labeled by the GIS IBiSA since 2010 under GPI "Grenoble Proteomic Infrastructure".
Synergistic effects of citrulline supplementation and exercise on performance in male rats: evidences for implication of protein and energy metabolisms. Goron A, Lamarche F, Cunin V, Dubouchaud H, Hourdé C, Noirez P, Corne C, Couturier K, Sève M, Fontaine E, Moinard C. Clin Sci (Lond). 2017 Mar 1.
Fractionation and proteomic analysis of the Walterinnesia aegyptia snake venom using OFFGEL and MALDI-TOF-MS techniques. Tarek Mohamed Abd El Aziz, Sandrine Bourgoin-Voillard, Stéphanie Combemale, Rémy Beroud, Mahmoud Fadl, Michel Seve and Michel De Waard. Electrophoresis. 2015 Oct;36(20):2594-605.
Quantitative Proteomic Approach to Understand Metabolic Adaptation in Non-Small Cell Lung Cancer. Martín-Bernabé A., Cortés R., Lehmann S.G., Seve M., Cascante M., Bourgoin-Voillard S. J Proteome Res. 2014;13(11):4695-704